Venous Thromboembolism Prophylaxis in Surgical Patients (2015-2018)
SUMMARY
Venous thromboembolism (VTE) prophylaxis in the surgical patient remains an important medical issue. Research has shown that VTE, which includes deep vein thrombosis and pulmonary embolism, occurs frequently in hospitalized patients who have undergone general, major gynecologic, major urologic, major orthopedic, or neurosurgery if preventive measures are not taken. Although it is impossible to predict with certainty which surgical patients will develop VTE, it is important for medical consultants to have a working knowledge of the different risk factors for VTE as well as current prophylaxis recommendations in order to employ appropriate strategies to reduce the risk of VTE. The following module discusses the clinical impact of VTE in surgical patients, reviews the various risk factors for VTE in surgical patients, and discusses prophylaxis options. In addition, goals for VTE prophylaxis and methods for evaluating when and how to initiate prophylaxis and determining the length of pharmacologic intervention are provided using recent research and the American College of Chest Physicians 2012 guidelines.
GOAL
To provide hospitalists with current data and guidelines regarding venous thromboembolism prophylaxis in surgical patients.
TARGET AUDIENCE
This activity is designed for hospitalists.
LEARNING OBJECTIVES
After completing the module, the participant should be able to:
- Recognize the clinical impact of venous thromboembolism (VTE) on surgical patients.
- Describe the risk factors that increase the likelihood of developing a VTE and how to risk stratify surgical patients based on these factors.
- Formulate the goals of prophylactic intervention programs.
- Summarize the VTE prophylaxis regimens for general and abdominopelvic surgery patients.
- Summarize the VTE pharmacoprophylaxis regimens for major orthopedic surgery patients.
- Outline when to initiate VTE chemoprophylaxis and the current roles of extended VTE chemoprophylaxis.
CME INFORMATION
Accreditation Statement:
This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of University of Virginia School of Medicine, ASiM, and the Society of Hospital Medicine. The University of Virginia School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.
Credit Designation Statement:
The University of Virginia School of Medicine designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Release date: February 27, 2015. Expiration date: February 27, 2018
Estimated time to complete activity: 2 hours
FACULTY & FACULTY DISCLOSURES
Full Disclosure Policy Affecting CME Activities:
The University of Virginia School of Medicine, as an ACCME accredited provider, endorses and strives to comply with the Accreditation Council for Continuing Medical Education (ACCME) Standards of Commercial Support, Commonwealth of Virginia statutes, University of Virginia policies and procedures, and associated federal and private regulations and guidelines on the need for disclosure and monitoring of proprietary and financial interests that may affect the scientific integrity and balance of content delivered in continuing medical education activities under our auspices.
The University of Virginia School of Medicine requires that all CME activities accredited through this institution be developed independently and be scientifically rigorous, balanced and objective in the presentation/discussion of its content, theories and practices.
All faculty presenters participating in an accredited CME activity are expected to disclose relevant financial relationships with commercial entities occurring within the past 12 months (such as grants or research support, employee, consultant, stock holder, member of speakers bureau, etc.). The University of Virginia School of Medicine will employ appropriate mechanisms to resolve potential conflicts of interest to maintain the standards of fair and balanced education to the participant. Questions about specific strategies can be directed to the Office of Continuing Medical Education, University of Virginia School of Medicine, Charlottesville, Virginia.
Leonard Feldman, MD (Chair)
Associate Professor of Medicine
Assistant Professor, School of Medicine
Division of General Internal Medicine,
Johns Hopkins University School of Medicine
Baltimore, Maryland
Dr Locke reports having no significant financial or advisory relationships with corporate organizations related to this activity.
Michael Streiff, MD
Associate Professor, Division of Hematology
Department of Medicine
Johns Hopkins University School of Medicine
Baltimore, Maryland
Dr Streiff reports receiving research support from Portola Pharmaceuticals, Inc; and receiving honoraria from Boehringer Ingelheim Pharmaceuticals, Inc, Daiichi Sankyo Company, Ltd, Janssen Healthcare, and Pfizer Inc.
The University of Virginia School of Medicine, as an ACCME provider, requires that all faculty presenters identify and disclose any off-label uses for pharmaceutical and medical device products. The University of Virginia School of Medicine recommends that each physician fully review all the available data on new products or procedures prior to clinical use.
Dr Locke reports discussing the following commercial products or services: apixaban, dabigatran, fondaparinux, low-molecular-weight heparin, rivaroxaban, and unfractionated heparin.
Dr Streiff reports discussing the following commercial products or services: use of low-molecular-weight heparin, unfractionated heparin in VTE prophylaxis, and perioperative bridging anticoagulation and the use of fondaparinux and rivaroxaban in VTE prophylaxis.
DISCLAIMER
INSTRUCTIONS
This activity is supported by independent educational grants from Boehringer Ingelheim Pharmaceuticals, Inc, Bristol-Myers Squibb Company, and Pfizer Inc.
Available Credit
- 2.00 AMA PRA Category 1 Credit™
- 2.00 Non-physician